- Zamora FC 1 Caroní FC 4
- Goles: Herlyn Cuica 15’ (ZFC) Carlos Muñoz 7’ Héctor García 70’ Anderson Betancourt 81’ y Cruz Maestre 90+3’ (CFC)
- Estudiantes FC 1 CD Lara 0
- Gol: Heiber Díaz 79′ (EDM)
- Yaracuyanos FC 1 Atlético El Vigía 1
- Goles: Walter Aguilar 82′ (YFC) Genlys Piñeros 37′ (AV)
- Caracas FC 2 Dvo Petare 2
- Goles: Josef Martínez 70′ y Luis Cabezas 76′ (CFC) Evelio Hernández 23′ y 85′ p (DP)
- Dvo Táchira 4 Zulia FC 0
- Goles: Sergio Herrera 29′ Jorge Rojas 37′ Ángel Farías en contra 45′ y Julio Gutiérrez 55′ (DT)
- Trujillanos FC 2 Aragua FC 0
- Goles: Goles: Norman Cabrera 36′ y Roberto Armúa 86′ p
- Atlético Venezuela 1 Dvo Anzoátegui 2
- Goles: Marcelo Refresquini 18′ (AV) Daniel Arismendi 6′ y 38’p (DA)
- Monagas SC 0 AC Mineros 0
- Carabobo FC 0 Real Esppor 0
CLASIFICACION TORNEO APERTURA 2010
| Nº | CLUBES | JJ | JG | JE | JP | GF | GC | PT | DG |
| 1 | Real Esppor | 14 | 10 | 2 | 2 | 27 | 8 | 19 | 32 |
| 2 | Dvo Táchira | 14 | 8 | 5 | 1 | 28 | 11 | 17 | 29 |
| 3 | Caracas FC | 13 | 8 | 2 | 3 | 19 | 12 | 7 | 26 |
| 4 | Dvo Petare | 14 | 7 | 5 | 2 | 23 | 17 | 6 | 26 |
| 5 | Trujillanos | 14 | 7 | 4 | 3 | 18 | 10 | 8 | 25 |
| 6 | Aragua FC | 14 | 7 | 3 | 4 | 19 | 17 | 2 | 24 |
| 7 | Anzoátegui | 14 | 6 | 4 | 4 | 29 | 26 | 3 | 22 |
| 8 | Yaracuyanos | 14 | 4 | 8 | 2 | 16 | 13 | 3 | 20 |
| 9 | A.C Mineros | 14 | 4 | 6 | 4 | 17 | 16 | 1 | 18 |
| 10 | Zulia FC | 13 | 5 | 3 | 5 | 18 | 21 | -3 | 18 |
| 11 | Estudiantes | 14 | 5 | 3 | 6 | 15 | 18 | -3 | 18 |
| 12 | Monagas SC | 14 | 4 | 4 | 6 | 22 | 20 | 2 | 16 |
| 13 | Carabobo | 14 | 2 | 6 | 6 | 13 | 20 | -7 | 12 |
| 14 | Venezuela | 14 | 3 | 3 | 8 | 16 | 27 | -11 | 12 |
| 15 | Zamora FC | 14 | 2 | 5 | 7 | 14 | 24 | -10 | 11 |
| 16 | El Vigía | 14 | 1 | 7 | 6 | 16 | 23 | -7 | 10 |
| 17 | C.D Lara | 14 | 1 | 6 | 7 | 15 | 26 | -11 | 9 |
| 18 | Caroní FC | 14 | 2 | 2 | 10 | 9 | 26 | -17 | 8 |
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